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Integrated Genomics
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  • Integrated Genomics

Integrated Genomics

TheIntegrated Genomics Shared Resourceat theGeorgia Cancer Centerprovides state-of-the-art technologies forDNA and RNA sequencingas well asspatial transcriptomics.

We offer a comprehensive suite of services, includingsample processingforfresh, frozen, and fixed cells or tissues,library preparation, andnext-generation sequencing (NGS)for bothbulk DNA/RNA sequencingandsingle-cell/nuclei sequencing. Forsingle-cell studies, we utilize theChromium X systemfrom10X Genomics. Our sequencing platforms, theIlluminaNovaSeq6000andNextSeq500, enablehigh-throughput, efficient sequencingfor a wide range of applications.

We have introducedsingle-cell spatial transcriptomicsusing theCosMxSMI platform, providing investigators with the ability to analyzesingle cells within their native tissue microenvironment. Additionally, we supportspatial transcriptomicswith theCytAssistinstrumentfrom10X GenomicsforVisiumspatial profiling.

Fornucleic acid and protein extraction, we utilize theQIAconnectsystemfromQiagen, ensuring high-quality sample preparation for downstream analyses.

Research Resource Identifier

To better track our publication history and ensure proper recognition, the Integrated Genomics Core has registered for a Research Resource Identifier (RRID) throughRRID Portal.

RRIDs are unique identifiers assigned to research tools, core facilities, model organisms, antibodies, and other scientific resources. Including an RRID in publications enhances transparency, reproducibility, and proper attribution, helping to track resource usage and increase visibility within the scientific community.

Researchers using the core are asked to include an acknowledgment statement in their manuscripts. If core members have provided significant scientific contributions, they should also be considered for co-authorship.

Please modify this acknowledgment statement as needed but ensure the RRID is included:"We acknowledge the support and contribution of the Integrated Genomics Core Shared Resources at the Georgia Cancer Center, Augusta University (RRID: SCR_026483)."

Jump to:Equipment & ServicesWhat We OfferContact Us

Contact Us

Genomics Core GCC

CN3156 E & F Labs

(706) 721-5471

Genomics Core GCC

Equipment & Services

Users are responsible for knowing how to run the equipment and what products and sample preparation to use.

All services are booked through iLABServices & Pricing

What We Offer

DNA Sequencing (inquire for more information)

E-mail for more information

Chip-Seq & Whole Transcriptome Seq

Read about chip sequencing and whole Transcriptome Sequencing. Chip-Seq & Whole Transcriptome Seq

miRNA (inquire for more information)

E-mail for more information

RNA-SeQ High & Low Input

For high input RNA we can work with a minim of 300ng of RNA & for the low input we can work with a minim of 25pg or 100 to 1000cell skipping RNA isolation. RNA-SeQ High & Low Input

Sample Purification

We house aQIAcubeConnectinstrument, afully automated systemdesigned for thepurification of nucleic acids and proteinsin molecular biology applications. This advanced system streamlinessample processing, ensuringhigh-quality, reproducible resultswith minimal hands-on time.

Engineered forprofessional users trained in molecular biology techniques, theQIAcubeConnectautomatesworkflows, enhancing efficiency and reducing variability.

Sample Purification

Sequencing Capabilities

About the NovaSeq 6000 System Sequencing Capabilities

Spatial Transcriptomic

Our currently has two different platforms that enable spatially resolved profiling. These are the Visium – 10X Genomics and the CosMx Spatial Molecular Imager (CosMx SMI) – Nanostring. More information below. Spatial Transcriptomic

Single Cell

The Chromium X Series instrument enables seamless scaling from pilot experiments through million-cell studies, and offers compatibility with an expanding range of Chromium Single Cell applications. This includes Single Cell Gene Expression Flex kits, which enable the most sensitive whole transcriptome profiling of fresh, frozen, and FFPE samples. Single Cell

Trainings (inquire for more information)

E-mail for more information

Quality Control Analysis

Information about our Agilent 2100 Bio analyzer, Agilent 2200 TapeStation, Qubit Fluorometer, NandoDrop 1000 Quality Control Analysis

Contact

photo of Martina Zoccheddu, MS

Martina Zoccheddu, MS

  • Director | CN 3305

(706) 721-5471

mzoccheddu@augusta.edu

photo of Miao Yu, PhD

Miao Yu, PhD

  • Research Manager | CN 3162

(706) 721-5471

miyu@augusta.edu

photo of Yali Zhu, PhD

Yali Zhu, PhD

  • Research Associate | CN 3162

(706) 721-5471

yazhu@augusta.edu

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