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Therapeutics Core

About

The mission of Augusta University Therapeutics Core (AUTC) is to provide an affordable on-campus service platform for the discovery of novel therapeutic targets and interventions for disease treatment. Our core facility is meticulously designed to foster the translation of basic scientific discoveries into pre-clinical drug development starting from target identification to high-throughput compound screening and biological validation. We offer tailored services that span from assay development to FDA-drug library screening, unbiased compound screening, and high-content imaging and screening to meet the diverse drug discovery needs of researchers. Our facility can empower researchers to repurpose existing FDA-approved drugs and discover new compounds for drug development, providing increased opportunities for extramural funding and patents.

Contact Us

Therapeutics Core

1462 Laney Walker Blvd., Augusta, GA 30912

Room CA4062

Monday - Friday 8:00AM – 5:00PM

Equipment

The core is equipped with state-of-the-art equipment, including a Biomek i7 automated liquid handler (Beckman), a PHERAstar microplate reader (BMG LabTech), and an ImageXpress® Micro Confocal High Content Imaging System (Molecular Devices), among other advanced tools.

Core equipment

Biomek

Services

The core has the following compound libraries: an FDA-approved drug library, a kinase inhibitor library, a GPCR ligand like compound library and a 100k unbiased compound collection. We provide the following services: 

  1. Consultation
  2. Assay Development
  3. Screening of an FDA-Approved Drug Library
  4. Screening of a kinase inhibitor library (or other specialized libraries)
  5. Pilot unbiased compound screening (up to 10k compounds)
  6. HTS (100k compounds)
  7. High-content imaging and screening
  8. Hit selection and validation

Contacts

photo of Qin Wang, MD, PhD, Professor

Qin Wang, MD, PhD, Professor

  • Director, AU Therapeutics Core

(706) 721-6285

qin.wang@augusta.edu

photo of Shalini Saggu, PhD, Assistant Professor

Shalini Saggu, PhD, Assistant Professor

  • Manager, AU Therapeutic Core

(706) 721-7025

ssaggu@augusta.edu

photo of Amy Trang, MS

Amy Trang, MS

  • Research Associate, AU Therapeutic Core

atrang@augusta.edu

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1120 15th Street, Augusta, GA 30912

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