Ruth Caldwell
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Cellular Biology and Anatomy
Medical College of Georgia
Department of Culver Vision Discovery Inst
Emeritus Faculty
Bio
I am a founding member of the Vascular Biology Center and the Vision Discovery Institute and VA Career Scientist. I have published over 140 peer reviewed articles and serve on numerous national review panels. My research is supported by grants from the NIH, VA and AHA. Our current focus is on the potential the urea cycle enzyme arginase as therapeutic target for diabetic retinopathy and other forms of ischemic retinopathy.
Education
-
Ph.D., Biopsychology.University of Memphis The, 1979
-
MS, BiopsychologyUniversity of Memphis The, 1976
-
BA, Mathematics, GeneralAgnes Scott College, 1964
Awards & Honors
-
Keith Green LectureshipVision Discovery Institute, 2021
-
VA Career Scientist2015
-
Fellow of the AHA2014
-
Excellence in Research Award2012
-
Excellence in Research Award2009
Courses Taught Most Recent Academic Year
Teaching Interests
Vascular Biology, Retinal Cell Biology
Scholarship
Selected Recent Publications
- Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function., 2023
Journal Article, Academic Journal
- Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization., 2023
Journal Article, Academic Journal
- Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy., 2022
Journal Article, Academic Journal
- Suppression of myeloid PFKFB3-driven glycolysis protects mice from choroidal neovascularization., 2022
Journal Article, Academic Journal
- Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy., 2022
Journal Article, Academic Journal
Research Interests
The current focus of our group’s research is on the potential of the superoxide generating enzyme NADPH oxidase and the urea cycle enzyme arginase as therapeutic targets for diabetic retinopathy and other forms of ischemic retinopathy.
Department Service
Professional Service
-
AHA/Vascular biology review group/reviewer2013 - Present
Role:Reviewer
-
VA IACUC2010 - Present
Role:Chairperson
-
NIH Grant Review2017 - 2018
Role:Committee Member
-
NIH National Eye Institute/Study Section/Ad hoc Review group member2012 - 2016
Role:Reviewer
